GLS2 and lung cancer: In all these studies, 968 was considered to perform as a GLS inhibitor, while its potential effect on GLS2 has not been investigated; however, considering the pro-oncogenic role of GLS2 in some types of cancer, e.g., lung cancer [73,75], it cannot be ruled out that the observed reduction in survival is, at least partially, also due to GLS2 inhibition.