CDKN2A and Pleural effusion: This panel has already been tested and successfully compared with BAP1 and p16 on two independent retrospective series: one including malignant (epithelioid PM) and benign pleural tissues, giving a sensitivity of 97% and a specificity of 100% [22], and the other including only pleural effusions (both cell blocks and stained smears) with a sensitivity and specificity both equal to 100% [23].