ALB and Osteopenia: Multivariate analysis showed that old age (odds ratio 3.02, 95% confidence interval 1.35–6.75, p < 0.01), adjuvant chemotherapy for a primary lesion before metachronous liver metastases (odds ratio 3.03, 95% confidence interval 1.20–7.67, p = 0.02), osteopenia (odds ratio 2.71, 95% confidence interval 1.19–6.15, p = 0.02), and low serum Alb level (odds ratio 2.34, 95% confidence interval 1.04–5.28, p = 0.04) were significant independent predictors of OVF (Figure 5).