PAX5 and precursor B-cell acute lymphoblastic leukemia: Some of these affected chromosomal regions where genes were previously shown to be altered in B-ALL, such as PAX5 at 9p13.2 (loss) [48,49,50], CDKN2A/B at 9p21.3 (loss) [49,50], and MYC at 8q24.21 [51] (Supplementary Table S2).