CTBP1 and non-small cell lung carcinoma: The treatment of NSCLC cells with nicotine increased the levels of the stress neurotransmitter noradrenaline, resulting in enhanced cell proliferation, an effect blocked by treatment with the α7nAChR antagonist α-BTX, or the non-selective β-blocker propranolol, which competitively antagonizes β-ARs [23].