Univariate Cox regression analysis revealed a significant correlation between the OS of HNSCC patients and several TCRRGs, namely CSF2, INPP5D, MAP2K1, MAP2K7, MAPK3, MAPK9, ORAI1, PIK3R3, PSMA1, PSMA7, PSMD10, PSMD2, PSMD7, SKP1, UBB, UBE2D2, and ZAP70 (Table 1). The gene discussed is SKP1; the disease is head and neck squamous cell carcinoma.