Univariate Cox regression analysis revealed a significant correlation between the OS of HNSCC patients and several TCRRGs, namely CSF2, INPP5D, MAP2K1, MAP2K7, MAPK3, MAPK9, ORAI1, PIK3R3, PSMA1, PSMA7, PSMD10, PSMD2, PSMD7, SKP1, UBB, UBE2D2, and ZAP70 (Table 1). Here, PSMD2 is linked to head and neck squamous cell carcinoma.