While there is no specific immunohistochemical marker exclusively for BSCs, Ber-EP4, which is typically strongly positive in Basal Cell Carcinomas (BCCs), and epithelial membrane antigen (EMA), which stains positively in Squamous Cell Carcinomas (SCCs), have been found to be helpful in the diagnostic process [2,5,18]. This evidence concerns the gene EPCAM and basal cell carcinoma.