Other IFN-related conditions, such as STING-associated vasculopathy with onset in infancy (SAVI) and tauopathies, including Alzheimer’s disease, both linked to dysregulated Type I IFN responses, warranting further research of C5aR2 in these contexts [38,39]. The gene discussed is C5AR2; the disease is early-onset autosomal dominant Alzheimer disease.