Stimulation of inward operation of NBCe1 in neocortical astrocytes upon brief chemical ischemia is in line with the proposed inward NBCe1 activity in cardiomyocytes upon myocardial ischemia [85] or in astrocytes exposed to long-lasting extracellular acidification to mimic cerebral ischemia [86]. This evidence concerns the gene SLC4A4 and myocardial ischemia.