With the aim of investigating more extensively the role of the Gal-9/Tim-3 pathway, Liu et al. and Wu et al. performed studies to assess the impact of blocking Gal-9 and Tim-3 interactions by treatment with alpha (α)-lactose on liver immunopathology during the erythrocytic stage of malaria in a P. berghei ANKA-infected mouse model [61,69]. This evidence concerns the gene HAVCR2 and malaria.