Of note, while a prior report demonstrated that a splice variant in TRPM1 was expressed more highly in the retina of late-stage AMD donor eyes and a second splice variant in TRPM1 was expressed in the RPE/choroid of AMD donor eyes [14], we did not find splicing for TRPM1 in the RPE/choroid. This evidence concerns the gene TRPM1 and age-related macular degeneration.