They also discovered that B-cell-rich tumors had a higher proportion of TCF7- or IL7R-expressing naïve or memory-like CD8+ and CD4+ T cells than B-cell-poor tumors, which suggested that a higher level of tumor-infiltrating B cells could recruit more progenitor T cells to TLSs and potentially lead to a better response to ICB. The gene discussed is CD4; the disease is neoplasm.