Similar to this finding, Kieffer et al. [86] discovered two subsets of myCAFs from breast cancer scRNA-seq data: ecm-myCAFs, which exhibited high expression of LRRC15 and were associated with ECM remodeling, and TGFβ-myCAFs, which had high expression of TGFβ1 and were associated with the TGF-β signaling pathway. Here, TGFB1 is linked to breast carcinoma.