The increased levels of TLR2 and MyD88 were also observed in kidney tissue (ANOVA: F(4, 10) = 50.64, P < 0.0001; F(4, 10) = 31.66, P < 0.0001, respectively) and in lung tissue (ANOVA: F(4, 10) = 44.01, P < 0.0001; F(4, 10) = 14.69, P < 0.0001, respectively) after CLP surgery (Fig. 9a–c), indicating that TLR2 and MyD88 are involved in the inflammation of sepsis in CLP mice. The gene discussed is MYD88; the disease is Sepsis.