Decreases in FUT2 expression and α-1,2-fucosylation were also noticed in the colon of patients with IBD such as ulcerative colitis (UC) or Crohn’s disease (CD) [10]; an increased expression of Lewis A antigen in the crypt epithelium of bowel tissues was also found in patients with deficiency in FUT2 synthesis [10]. This evidence concerns the gene FUT2 and Crohn disease.