As an example, Musunuru et al. [10] reported that the noncoding polymorphism site rs12740374 located at the C/EBP (CCAAT/enhancer binding protein) binding site on 1p13 affected the binding of C/EBP to DNA, thereby altering the expression of the Sortilin 1 (SORT1) gene and increasing the risk of myocardial infarction. This evidence concerns the gene SORT1 and myocardial infarction.