METTL3 and renal fibrosis: METTL3 plays a crucial role in obstructive nephropathy, and one study revealed a future therapeutic strategy for obstructive nephropathy, in which METTL3 can promote MALAT1 expression, which was associated with binding and inhibiting miR-145, leading to the upregulation of FAK and ultimately to the exacerbation of renal fibrosis.