Regarding admission laboratory indicators, patients with AP who received antibiotics exhibited higher levels of PCT (3.8 ± 7.9 vs. 1.2 ± 3.2, P < 0.001), CRP (120.4 ± 103.9 vs. 79.5 ± 81.6, P < 0.001), serum amylase (1229.02 ± 1132.42 vs. 902.5 ± 940.4, P < 0.039), blood creatinine (93.0 ± 73.2 vs. 74.2 ± 39.1, P < 0.001), and blood calcium (2.0 ± 0.2 vs. 2.0 ± 0.1, P < 0.001) compared to patients in the non-antibiotic group. The gene discussed is CRP; the disease is alkaline phosphatase measurement.