Upon admission, patients with AP who received antibiotics exhibited higher levels of PCT (4.7 ± 10.8 vs 1.1 ± 2.6, P < 0.001), CRP (144.2 ± 125.2 vs 89.4 ± 102.4, P < 0.001), serum amylase (954.6 ± 1316.8 vs 693.0 ± 827.3, P < 0.003), total bilirubin (30.4 ± 36.8 vs 26.8 ± 24.1, P < 0.021), blood creatinine (92.7 ± 79.2 vs 73.4 ± 40.0, P < 0.001), and triglycerides (8.3 ± 15.0 vs 5.4 ± 9.3, P < 0.001) compared to the non-antibiotic group. The gene discussed is CRP; the disease is alkaline phosphatase measurement.