We first compared BACH1 mRNA levels in purified peripheral blood CD14+ monocytes obtained from Brazilian PTB patients (respiratory symptoms suggestive of TB for more than 2 weeks and culture positive for Mtb (MGIT or solid media)) with patients with no symptoms, normal chest X-ray, but with positive IGRA tests (TBI) and healthy control (HC) individuals. Here, BACH1 is linked to tuberculosis.