Using unsupervised analysis of DNA methylation tumour profiles, DMG_K27-BRAF/FGFR1 formed a specific cluster, separated from other DMG_K27 gliomas, others adult/paediatric diffuse gliomas, low-grade glial/glioneuronal tumours and more specifically BRAFV600E-mutated ganglioglioma even midline located. The gene discussed is FGFR1; the disease is central nervous system cancer.