The rapid blood clearance of [99mTc]Tc-EDDA/HYNIC-iPSMA is maintained with [99mTc]Tc-PSMA-GCK01 but the slight predominant hepatobiliary route of excretion of [99mTc]Tc-PSMA-GCK01 might allow a better diagnostic performance of local relapse or perivesical lymph node metastasis [22] since tracer retention in the bladder might complicate the proper discrimination of perivesical lesions. The gene discussed is FOLH1; the disease is metastatic malignant neoplasm in the lymph nodes.