Among all the herbal samples, TOPSIS analyses indicated that (i) CSA exhibited the highest overall results for TPC, antioxidant potential, and enzyme inhibition; (ii) BM possessed high potential to inhibit diabetes through α-amylase and α-glucosidase inhibition; (iii) BM and DM exhibited the highest ACE inhibition, leading to the control of hypertension; and (iv) DL retarded Alzheimer’s disease progression through cholinergic (AChE and BChE inhibitions) and β-amyloid formation (BACE-1 inhibition). Here, ACHE is linked to Hypertension.