In breast invasive carcinoma no predictive value was observed by SLC6A14, SLC12A4 or SLC25A15 alone, but there was a nonsignificant trend for reduced survival in SLC6A14-high combined with SLC12A4-high or SLC25A15-high expression (Extended Data Fig. 7b). This evidence concerns the gene SLC6A14 and invasive breast carcinoma.