On comparing the PD-L1 positivity of subepithelial TAFs, 4/11 cases of mild dysplasia and 14/14 moderate/severe dysplasia cases exhibited PD-L1 positivity which was statistically significant (p value < 0.001) .The mean SID score of PD-L1 positive TAFs were more in moderate/severe dysplasia compared to mild dysplasia which was found to be statistically significant (p value: 0.000). The gene discussed is CD274; the disease is dysplasia.