However, a report of patients with TCR MM from Mayo Clinic showed that among the 44% of patients with FISH testing repeated at the time of TCR status, 87% were high-risk (defined at the presence of t(4;14), t(14;16), t(14;20), del(17p), TP53 mutation, and gain(1q)). Here, TP53 is linked to Miyoshi myopathy.