SELL and malignant colon neoplasm: Furthermore, l-selectin and its ligands also participate in the adhesion of the blastocyst to the maternal interface of the uterine endometrium.[44] Relevant studies have demonstrated that SELL expression is significantly increased at the lesion site, correlating with the infiltration and metastasis of inflammatory cells.[45]l-Selectin ligands have been found to impact the progression of colon cancer.[46] Therefore, it is speculated that SELL may play important roles in the inflammation and immune response process of UC.