Several disease-associated TCRβ sequences were only expressed in new-onset T1D samples: one CD4 PPI-specific (#16), two CD8 PPI-specific (#63 and #64), and two CD8 ZnT8-specific TCRβs (#71 and #72) were expressed only in that cohort and not in at-risk cases. The gene discussed is CD4; the disease is type 1 diabetes mellitus.