In the older population, for patients over 15 years of age at the time of cancer diagnosis, it has been reported that the risk of ovarian insufficiency increases with age.22 Additionally, the postchemotherapy level of AMH has been shown to decrease with advancing age at diagnosis in adult breast cancer.23 This suggests that the effect of age on ovarian function decreases due to cancer treatment and may differ in ovarian development status in the pediatric or adolescent population and adult cancer patients. The gene discussed is AMH; the disease is cancer.