Upon activation, CTLs can eliminate tumor cells by producing antitumor cytokines like IFN‐γ.[26b] We evaluated IFN‐γ levels in activated CD8+T cells using an ELISPOT kit and observed that the DMPtNPS + RT group had 2.2‐fold increased IFN‐γ spots per 105 cells compared to RT alone (Figure 3L and Figure S12, Supporting Information). Here, CD8A is linked to neoplasm.