IL1B and neoplasm: Moreover, cytokines such as IL‐1β, IL‐10, IL‐4, and TGF‐β also increased (Figure 5F and Figure S17E–H, Supporting Information), which may promote tumor growth through inflammation.[27] In addition, GSEA analysis demonstrated that the DMPtNPS + RT group had enrichment of pathways associated with negatively regulating T cell differentiation, proliferation, and TCR signaling compared to RT alone using GSEA.