GPT and breast cancer: demonstrated that the released Zn2+ from Zn‐LDH nanomedicines could also induce ICD by activating the cGAS‐STING signaling pathway, promoting DC maturation and activating antitumor immune responses of cytotoxic CD8+ T cells (Figure 8).[126] No evident changes in body weight and the levels of alanine transaminase (ALT) and aspartate aminotransferase (AST) in different groups in melanoma or breast cancer models indicated the safety of metalloimmunotherapy.