demonstrated that the released Zn2+ from Zn‐LDH nanomedicines could also induce ICD by activating the cGAS‐STING signaling pathway, promoting DC maturation and activating antitumor immune responses of cytotoxic CD8+ T cells (Figure 8).[126] No evident changes in body weight and the levels of alanine transaminase (ALT) and aspartate aminotransferase (AST) in different groups in melanoma or breast cancer models indicated the safety of metalloimmunotherapy. Here, GPT is linked to melanoma.