LCORL and major depressive disorder: For instance, GBE1 and PIP4K2A were associated with sensitivity to environmental stress and adversity at the genome level; CTBP2P3 was associated with depression severity × hours spent watching television interaction at the genome level; LCORL was related to general cognitive ability at the genome level and intelligence at the transcriptome level; and EPB41L1 was associated with intellectual developmental disorder at the protein level.