TLR9 and neoplasm: Some Toll‐like receptor ligands, such as imiquimod, a TLR7 agonist, and CpG, a TLR9 ligand, can directly induce apoptosis of TLR positive tumor cells, or enhance tumor‐infiltrating innate immune cells and tumor specific T‐cell functions.69, 70, 71, 72, 73, 74