For example, TOB1 predicted the prognosis in KIRC, LGG, MESO, PAAD, PCPG, PRAD, SARC, UCEC and UVM patients, and TOB2 predicted poor prognosis in COAD, GBM, KIRC, LGG, PAAD patients. This evidence concerns the gene TOB2 and colon adenocarcinoma.