HLA-A and neoplasm: The WT and DKO clones of H1, an HLA-A*02:01 positive (A*0201pos) PSC line, and ESI017, an HLA-A*02:01 negative (A*0201neg) PSC line, were transduced with a lentiviral vector encoding the α- and β-chains of the HLA-A*02:01-restricted 1G4 TCR specific for the tumour-associated NYESO157–165 peptide (hereafter, WT + TCR and DKO + TCR PSCs, respectively)19,20.