Meanwhile, such a pre-incubation with NSCLC efficiently elevated the frequency of FOXP3-expressing T cells and decreased the frequencies of T-bet+, GATA3+, and RORγt+ T cells (Fig. 1A, B), suggesting an inhibitory effect on Teff cells and an advancing effect on Treg cells. The gene discussed is FOXP3; the disease is non-small cell lung carcinoma.