Interestingly, C1498FF–B7-1–mPD-1H tumor grew faster in vivo than C1498FF–B7-1 tumor (mean radiance of C1498FF–B7-1 versus C1498FF–B7-1–PD-1H on day 21: 4.6 × 105 versus 5.3 × 107, n = 3 per group, P = 0.01) (Supplemental Figure 6B). The gene discussed is CD80; the disease is neoplasm.