For example, within vascular tissues (Figure 3A), we find a number of genes such as NCAM1, MYLK, and ACTA2, all of which have previously shown to have a link with CAD but with limited validation (Erbilgin et al., 2018; Ghosh et al., 2015; Wang et al., 2007; Yuan, 2015). Here, ACTA2 is linked to coronary artery disorder.