Using the log-rank test for univariate survival analysis of prognosis in all patients with LN, we found that the positivity of anti-dsDNA IgE autoantibodies was not a risk factor for composite outcomes, including primary and secondary endpoints (hazard ratio (HR), 1.961; 95% confidence interval (CI), 0.487–7.887; p = .343). This evidence concerns the gene IGHE and lobular neoplasia.