EGFR and lip and oral cavity carcinoma: Exosomes derived from oral cancer cell contain NAP1 that enhanced the cytotoxicity of NK cells.53 Exosomes derived from oral squamous cell carcinomas also contain the biomarker EGFR.54 Most often EGFR and CD 9 are in the same exosome.55 The EGFR secreted by OSCC cells play a vital role in the EMT of epithelial cells.