Figure 2 shows descriptive data on the development of serial glucose concentrations and Fig. 3 shows mean insulin units per day for the six predefined strata (i.e., wave 1 without [1] and with [2] diabetes mellitus; the second wave without [3] and with [4] diabetes mellitus with low HbA1c and without [5] and with [6] diabetes mellitus with high HbA1c). The gene discussed is INS; the disease is diabetes mellitus.