Immune infiltration analysis revealed that various immune cells were infiltrated in TIME and that PCa patients with high HOXC13 expression were accompanied by low infiltration of tumor-killing immune cells (γδ T cells and plasma cells) and monocytes, while promoting high infiltration of tumor promoting immune cells (M2 macrophages) (Fig. 7A and B). This evidence concerns the gene HOXC13 and posterior cortical atrophy.