To understand the ICP expressions in T-cell subsets and their relationship with intratumoral clonality, we analyzed transcriptomes, including TCR sequences, in enriched CD45 + cells from five freshly resected tumors (2 NSCLCs, 1 HCC, 1 HNSCC, and 1 EOC) using droplet-based single-cell RNA sequencing (scRNA-Seq, 10X Genomics). The gene discussed is PTPRC; the disease is hepatocellular carcinoma.