MTOR and neoplasm: LXI-15029 can bind to mTOR proteins potently, significantly, or completely inhibiting the phosphorylation of the mTORC1 substrates S6K1 T389, S6 S235/236, and 4E-BP1 T70, as well as the phosphorylation of the mTORC2 substrate AKT S473, thereby inhibiting the growth of tumor cells.