To understand the potential biological roles and related pathways of CCL2 involved in GBM pathogenesis, we took advantage of the TCGA data and analyzed the correlation between CCL2 and other genes in GBM, and then performed functional enrichment analysis of the top 370 genes which were most positively associated with CCL2 (p < 0.05, Spearman’s correlation coefficient > 0.5, Fig. S5A-C, Table S1). Here, CCL2 is linked to glioblastoma.