MAPK3 and non-small cell lung carcinoma: Consistent with our previous findings, we show here that the exposure of either HMC-1 (Fig. 1) or LAD-2 cells (Fig. 2) to membranes derived from the H1299 NSCLC cell line resulted a significant increase in the phosphorylation of ERK1/2 (p < 0.05), and that this effect was significantly inhibited by the MEK inhibitor U0126 (p < 0.01).