Furthermore, the frequent detection of FABP4+ lipogenic fibroblast-like cells in low-grade well differentiated tumors, plus their absence in high-grade poorly differentiated tumors (Fig. 8j, k), associates lipogenic fibroblasts with benign tumors and less activated stroma, consistent with the finding that FABP4 is one of the top stromal markers that predict good patient prognosis17. This evidence concerns the gene FABP4 and benign neoplasm.