Furthermore, SNHG16 holds potential as a biomarker for distinguishing COVID-19 cases from healthy controls with an AUC of 0.67, sensitivity of 0.70, and specificity of 0.59.161 CircRNA has_circ_0000479 also showed upregulation in the COVID-19 patients, with a negative correlation with IL-6 expression.114. The gene discussed is IL6; the disease is COVID-19.