GPT and metabolic dysfunction-associated steatohepatitis: In another clinical study, the treatment of Lactobacillus bulgaricus and Streptococcus thermophilus drastically decreases the levels of ALT, aspartate aminotransferase (AST) and γ-glutamyltransferase in patients with NASH (Table 2).332 In addition, some probiotics also display effectiveness for the treatment of persistent gastrointestinal symptoms and depression in patients with IBS333,334 neurophysiological patterns in patients with ASD,335 and other depressive symptoms.336,337