,3,4,5 Later, Duffy blood groups were identified,6,7 and it was demonstrated that the absence of the Duffy antigen receptor for chemokines (DARC) on the surface of human erythrocytes, caused by a single-point mutation in the GATA-1 promoter sequence of ackr1−, was associated with natural resistance to vivax malaria.8 Here, ACKR1 is linked to Plasmodium vivax malaria.