Our findings revealed that TMEM150A overexpression in GBM tissues was strongly correlated with immune, estimate, and stromal scores, and significantly correlated with tumour purity, Th1 cells, NK cells, NK CD56dim cells, cytotoxic cells, CD4+ T cells, T cells, aDCs, DCs, eosinophils, iDCs, macrophages, neutrophils, Tmems, Th17 cells, Th2 cells, and Tregs. This evidence concerns the gene CD4 and neoplasm.