It was displayed that VEGFA, Wnt-1, and β-catenin expression levels in ESCC cells significantly were reduced, and the phosphorylation of β-catenin and AAK1 were stimulated upon upregulating miR-29c-3p, while silencing miR-29c-3p yielded the reverse results (Fig. 3d). The gene discussed is VEGFA; the disease is esophageal squamous cell carcinoma.